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Title: Clinical Outcomes In Patients Using A Spinal Cord Stimulation System With Multiple Neurostimulative Modalities For Chronic Pain: Initial Real World Experience From Europe
e-poster Number: INSIM5
Category: Pain
Author Name: Jan Willem Kallewaard
Institute: Rijnstate Hospital
Co-Author Name: Pasquale De Negri, JF Paz-Solis, Simon Thomson, MA Canos-Verdecho
Abstract :
Background: Spinal Cord Stimulation (SCS) systems equipped with several available modalities of neurostimulation such as multiple waveforms, customized field shape programming, and simultaneous or sequential pulse trains are designed to provide for robust customization of treatment for chronic pain.
Methods/Materials: This is an observational case-series conducted in Europe as part of an ongoing retrospective chart review evaluation of SCS outcomes for chronic pain (Clinicaltrials.gov identifier: NCT01550575). Patients were implanted with an SCS system (Precision Spectra WaveWriter, Boston Scientific) capable of combination therapy, multiple waveforms and advanced field shapes, and waveform automation. Assessments collected include (but not limited to) baseline characteristics (demographics, medical history, pain diagnosis), pre- and post-implant pain intensity (NRS), and quality-of-life (EQ-5D-5L) scores.
Results: To date, 91 patients analyzed demonstrate a mean overall baseline NRS pain score of 7.9±1.8, and a mean follow-up duration of 118 days. At 3-months follow-up, a mean 5.2-point reduction in NRS score from baseline was observed (mean NRS: 2.6, p<0.0001) in a sub-set reporting low back pain (n=51). Fifty-one percent of patients who reached their 3-month follow-up reported a pain score of 2 or less. Patients evaluated for Quality of Life (EQ-5D-5L) demonstrated significant improvement at their last follow-up (n=19) compared to baseline assessment. On-going data collection is occurring and additional results will be presented.
Discussion/Conclusion: The capability of Spinal Cord Stimulation systems equipped with several available modalities of neurostimulation such as multiple waveforms, advanced/customizable field shape programming, and combination therapy is particularly clinically relevant given the established dynamic nature of chronic pain.
