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Title: Morphometric Analysis Of Subthalamic Nuclei In Patients Of Deep Brain Stimulation In Parkinson's Disease
e-poster Number: INSIM104
Category: Neurosurgery
Author Name: Sonal Chauhan
Institute: National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru
Co-Author Name: Dwarakanath Srinivas
Abstract :
Introduction -
Deep brain stimulation (DBS) is the dominant surgical intervention for Parkinson disease (PD) because of its reversibility, adjustability, and applicability for bilateral intervention. Conventional methods employ standard atlas coordinates to target the STN. However, the positions and sizes of the nuclei may be more variable than the standard atlas.
Methods -
We retrospectively analyzed morphometry of all the patients with PD who underwent STN-DBS at NIMHANS and determined the location of electrode contacts in the AC-PC space.
Results -
Accurate localization of the DBS electrode was identified and its statistical significance with respect to other studies was investigated.
Conclusions -
Individual variations exist in the location of the STN target. This study demonstrates the morphometric variability of subthalamic nuclei in patients who underwent STN-DBS.